Upstream Bio Phase 2 Trial Shows Verekitug Cuts Severe Asthma Flares 56%
Upstream Bio presented Phase 2 VALIANT results for verekitug in severe asthma at ERS Congress 2026. Dosing 100 mg every 12 weeks reduced AAER by 56% versus placebo in patients with severe asthma, with favorable safety and improvements in lung function and inflammatory biomarkers. The company plans to start Phase 3 in severe asthma and CRSwNP in Q1 2027.