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Tyra Biosciences Reports Positive Phase 2 SURF302 Results for Dabogratinib

Tyra Biosciences logoTyra Biosciences
Sig2.30Sen+0.53Env0.00Soc+1.55Gov0.00

Tyra Biosciences reported initial Phase 2 SURF302 results for oral dabogratinib in low-grade IR NMIBC. In combined lesion cohorts, it showed 79% ORR with a 64% CR rate at 60 mg once daily, and in single-marker lesions 100% ORR with 75% CR (n=8). Safety appeared favorable, with Grade 3 TEAEs in 14% (60 mg) and 9% (50 mg), supporting planned adjuvant Phase 3 strategy.

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