TScan Reorganizes to Prioritize In Vivo Solid-Tumor TCR-T Programs
TScan Therapeutics will strategically reorganize to prioritize its in vivo solid-tumor program, advancing two engineered TCR-T candidates to IND-enabling studies and planning Phase 1 in Q4 2027. It reports Cohort C Phase 1 ALLOHA data showing complete donor chimerism in 13/13 tracked patients. The company pauses further Phase 3 ALLOHA-2 enrollment due to insufficient capital, while continuing patient tracking, and seeks collaboration partners for its heme and autoimmune programs.
Coverage (7)
- TScan Therapeutics Cuts 75% of Staff, Pivots to In Vivo TCR-T for Solid Tumors (biopharminternational.com)
- TScan cuts 75% of workforce while shifting focus to solid tumor program (biospace.com)
- TScan Therapeutics cuts 75% of workforce, pauses Phase 3 ALLOHA-2 trial for TSC-101 (clinicaltrialvanguard.com)
- TScan axes 75% of workforce to make room for solid tumor programs (fiercebiotech.com)
- TScan Therapeutics Cuts Workforce by 75% and Shifts Focus to Solid Tumor Program (investorshub.advfn.com)
- TScan Therapeutics Announces Strategic Reorganization to Focus on in vivo Cell Therapy for Solid Tumors (globenewswire.com)
- TScan Therapeutics Pauses Phase 3, Reduces Workforce ~75% (stocktitan.net)