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Novartis Reports Phase 3 Drug Trials Fail Primary Endpoints, Shares Drop

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Novartis shares fell more than 12.5% at the open on September 8, 2026, after the company said its Phase 3 HARBOR study of del-desiran and Phase 3 HORIZON study of pelacarsen did not meet their primary endpoints. Pelacarsen’s failure was disclosed after market close on September 4, and del-desiran’s failure was announced before the market opened on September 8. Shareholders may seek review of losses through SueWallSt.

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