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Novartis’ Phase 3 trials fail for del-desiran and pelacarsen

Novo Nordisk logoNovo Nordisk
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Novartis logoNovartis
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Novartis reported two Phase 3 setbacks: del-desiran failed to improve outcomes in myotonic dystrophy type 1, dashing hopes for a key Avidity Biosciences buyout asset. Its antisense therapy pelacarsen also showed no significant benefit on cardiovascular risk in a late-stage study, adding pressure on the company’s broader development pipeline.

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