nytimes.com

Novartis’ Experimental Pelacarsen Fails in Heart Disease Prevention

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Sig3.09Sen-5.69Env0.00Soc-1.08Gov-0.25

Novartis said its experimental drug pelacarsen, designed to block lipoprotein(a), failed. The drug was widely expected to help prevent heart attacks, strokes, and cardiovascular deaths, building on evidence from studies suggesting Lp(a) lowering could be protective. Cardiologists described the result as extremely disappointing, with no additional trial details provided.

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