Novartis Enrolls First Patient in Phase 3 PRESERVE PSP Trial
Novartis said the first participant has been enrolled in its Phase 3 PRESERVE trial of NIO752 for a form of progressive supranuclear palsy (PSP). The antisense oligonucleotide is intended to reduce tau levels and is given as four spinal injections over three months. Earlier Phase 1/2 results showed biomarker stabilization at high doses.