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Novartis DM1 Drug Del-desiran Misses Phase III Primary Endpoint

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Sig2.85Sen-3.15Env0.00Soc-1.90Gov0.00

Novartis said its experimental DM1 treatment del-desiran missed the Phase III primary endpoint, though other analyses suggested some clinical activity. Safety was generally consistent with prior data. The company will review the full dataset and discuss next steps with health authorities, while noting no approved DM1 therapies remain and daily burdens continue for patients.

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