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Ionis Shares Drop After Pelacarsen Phase 3 Misses Primary Endpoint

Ionis Pharmaceuticals logoIonis Pharmaceuticals
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Pelacarsen’s Phase 3 Lp(a)HORIZON study missed its primary endpoint, and Ionis Pharmaceuticals shares fell 13.1% in premarket trading. The result by Novartis reduces prospects for commercial payments Ionis could receive under its pelacarsen licensing deal. No updated remaining-payment estimate was provided, and a separate eplontersen Phase 3 also missed its goal earlier.

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