Celltrion Wins Korea Phase 3 OK for Darzalex Biosimilar; U.S. Phase 3 for Keytruda
Celltrion said South Korea’s Ministry of Food and Drug Safety approved a Phase 3 protocol amendment for CT-P44, its Darzalex biosimilar, covering a two-year, 394-patient study in refractory or relapsed multiple myeloma with randomization to a CT-P51 arm versus the Keytruda arm. The company also reported the FDA cleared a Phase 3 protocol amendment for CT-P51, enrolling 220 patients with previously untreated metastatic non-squamous non-small cell lung cancer. Darzalex generated about $14.35B in global net sales last year.