Bristol Myers Ends Cellares Deal to Manufacture Breyanzi CAR T
Bristol Myers Squibb ended its commercial-scale manufacturing partnership with Cellares for Breyanzi CAR T-cell therapy after concluding that Cellares’ automated Cell Shuttle platform could not meet the requirements of Breyanzi’s approved process. The news also highlights faster sickle cell gene-therapy collection methods and preclinical CAR T advances involving Regnase-1 deletion and CD40 stimulation.