BioNTech and Genentech terminate BNT122 phase 2 colorectal cancer trial
BioNTech and Genentech ended a phase 2 study of autogene cevumeran (BNT122) in patients with surgically removed stage 2 or 3 colorectal cancer after an independent Data Safety Monitoring Board identified a reason to stop the trial. The program was testing whether the personalized vaccine could prevent recurrence. A separate phase 2 BNT122 trial with immunotherapy remains ongoing.