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BioCryst Turns Profitable in 2025 as Rare-Disease Assets Draw Suitors

BioCryst Pharmaceuticals logoBioCryst Pharmaceuticals
Sig2.25Sen+3.60Env0.00Soc0.00Gov0.00

BioCryst reported its first full year of profitability in 2025, and Q2 2026 revenue rose 34% to $218 million. With market cap around $2.5 billion, the shares have drawn acquisition speculation, with Takeda and AstraZeneca cited as top potential buyers given concerns around competing rare-disease assets. Orladeyo generated $158.2 million in Q2 2026 revenue, and BioCryst recently closed the Astria Therapeutics deal to add navenibart.

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